Authors
Alessandro Invernizzi, Alessandro Torre, Salvatore Parrulli, Federico Zicarelli, Marco Schiuma, Valeria Colombo, Andrea Giacomelli, Mario Cigada, Laura Milazzo, Annalisa Ridolfo, Ivano Faggion, Laura Cordier, Marta Oldani, Sara Marini, Paolo Villa, Giuliano Rizzardini, Massimo Galli, Spinello Antinori, Giovanni Staurenghi, Luca Meroni
Publication date
2020/10/1
Journal
EClinicalMedicine
Volume
27
Publisher
Elsevier
Description
Background
Coronavirus disease 2019 (COVID-19) has been associated to microvascular alterations. We screened the fundus of patients with COVID-19 to detect alterations of the retina and its vasculature and to assess possible correlations with clinical parameters.
Methods
Cross-sectional study. The presence of retinal alterations in patients with COVID-19 and subjects unexposed to the virus was assessed using fundus photographs and their prevalence was compared. Mean arteries diameter (MAD) and mean veins diameter (MVD) were compared between patients and unexposed subjects with multiple linear regression including age, sex, ethnicity, body mass index, smoking/alcohol consumption, hypertension, hyperlipidaemia, diabetes as covariates. The influence of clinical/lab parameters on retinal findings was tested in COVID-19 patients.
Findings
54 patients and 133 unexposed subjects were enrolled …
Scholar articles
A Invernizzi, A Torre, S Parrulli, F Zicarelli, M Schiuma… - EClinicalMedicine, 2020