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The Polop Alto valley, in eastern Spain, serves as the focus of a study of long-term temporal and spatial dynamics in human land use. The data discussed here derive from intensive, pedestrian, non-site survey. We employ the concept of artifact taphonomy to assess the various natural and cultural processes responsible for accumulation and distribution patterns of artifacts. Our results suggest that the most significant land-use changes in the Polop Alto took place at the end of the Pleistocene and accompanying the late Neolithic, while much less notable changes in land-use patterns are associated with the Middle-Upper Paleolithic transition and the initial use of domestic plants and animals in the valley.