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Recently, directing-group-assisted activation of ortho aromatic CÀH bonds, and subsequent CÀC bond formation by coupling with organic halides or organometallic reagents have been reported.[1] A variety of directing groups, such as acetyl, acetamino, carboxylic acid, oxazolyl, pyridyl, and imino moieties have been used for CÀH bond activation.[2] Aside from the above functional groups, a few examples have been reported using oximes as directing groups for CÀH bond activation. Thus, Bezsoudnova and Ryabov reported the isolation of an ortho-palladated aryl oxime from benzaldehyde oximes and a palladium complex.[3] Sanford and coworkers reported a palladium-catalyzed O-methyl oximedirected activation of sp2 and sp3 CÀH bonds, followed by oxygenation with ozone and PhI (OAc) 2.[4a, b] In 2006, Che and co-workers reported the ortho amidation of O-methyl oxime by palladium-catalyzed CÀH …