Authors
EU Arabidopsis Genome Project, M Bevan, I Bancroft, E Bent, K Love, H Goodman, C Dean, R Bergkamp, W Dirkse, M Van Staveren, W Stiekema, L Drost, P Ridley, S-A Hudson, K Patel, G Murphy, P Piffanelli, H Wedler, E Wedler, R Wambutt, T Weitzenegger, TM Pohl, N Terryn, J Gielen, R Villarroel, R De Clerck, M Van Montagu, A Lecharny, S Auborg, I Gy, M Kreis, N Lao, T Kavanagh, S Hempel, P Kotter, K-D Entian, M Rieger, M Schaeffer, B Funk, S Mueller-Auer, M Silvey, R James, A Montfort, A Pons, P Puigdomenech, A Douka, E Voukelatou, D Milioni, P Hatzopoulos, E Piravandi, B Obermaier, H Hilbert, A Düsterhöft, T Moores, JDG Jones, T Eneva, K Palme, V Benes, S Rechman, W Ansorge, R Cooke, C Berger, M Delseny, M Voet, G Volckaert, H-W Mewes, S Klosterman, C Schueller, N Chalwatzis
Publication date
1998/1/29
Journal
Nature
Volume
391
Issue
6666
Pages
485-488
Publisher
Nature Publishing Group UK
Description
The plant Arabidopsis thaliana (Arabidopsis) has become an important model species for the study of many aspects of plant biology. The relatively small size of the nuclear genome and the availability of extensive physical maps of the five chromosomes,, provide a feasible basis for initiating sequencing of the five chromosomes. The YAC (yeast artificial chromosome)-based physical map of chromosome 4 was used to construct a sequence-ready map of cosmid and BAC (bacterial artificial chromosome) clones covering a 1.9-megabase (Mb) contiguous region, and the sequence of this region is reported here. Analysis of the sequence revealed an average gene density of one gene every 4.8 kilobases (kb), and 54% of the predicted genes had significant similarity to known genes. Other interesting features were found, such as the sequence of a disease-resistance gene locus, the distribution of retroelements, the …
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EU Arabidopsis Genome Project, M Bevan, I Bancroft… - Nature, 1998