Authors
Marc de Perrot, John T Granton, Karen McRae, Marcelo Cypel, Andrew Pierre, Thomas K Waddell, Kazuhiro Yasufuku, Michael Hutcheon, Cecilia Chaparro, Lianne Singer, Shaf Keshavjee
Publication date
2011/9/1
Journal
The Journal of heart and lung transplantation
Volume
30
Issue
9
Pages
997-1002
Publisher
Elsevier
Description
BACKGROUND
Our management of patients with idiopathic pulmonary arterial hypertension (iPAH) awaiting lung transplantation changed in 2006 with the introduction of extracorporeal life support (ECLS) as an option to bridge these patients to transplantation (BTT).
METHODS
To study the effect of this change on waiting list mortality and post-transplant outcome, 21 consecutive iPAH patients listed for lung transplantation between January 2006 and September 2010 (second cohort) were compared with 23 consecutive iPAH patients listed between January 1997 and December 2005 (first cohort).
RESULTS
Between the first and second cohort, the number of patients admitted to the hospital as BTT increased from 4% (1 of 23) to 48% (10 of 21; p = 0.0009). Six patients were BTT with ECLS in the second cohort, including 4 with the Novalung device (Novalung GmbH, Hechingen, Germany) connected as a pumpless …
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M de Perrot, JT Granton, K McRae, M Cypel, A Pierre… - The Journal of heart and lung transplantation, 2011