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The use of metamodeling techniques in the design and analysis of computer experiments has progressed remarkably in the past two decades, but how far have we really come? This is the question that we investigate in this paper, namely, the extent to which the use of metamodeling techniques in multidisciplinary design optimization have evolved in the two decades since the seminal paper on Design and Analysis of Computer Experiments by Sacks et al. As part of this review, we examine the motivation for advancements in metamodeling techniques from both a historical perspective and the research itself. Based on current thrusts in the field, we emphasize multi-level/multi-fidelity approximations and ensembles of metamodels, as well as the availability of metamodels within commercial software and for design space exploration and visualization in this review. Our closing remarks offer insight into future research …