Authors
N Emaus, CG Gjesdal, B Almås, M Christensen, AS Grimsgaard, GKR Berntsen, L Salomonsen, V Fønnebø
Publication date
2010/10
Journal
Osteoporosis international
Volume
21
Pages
1731-1740
Publisher
Springer-Verlag
Description
Summary
Vitamin K2 may preserve bone strength and reduce fracture risk. In this randomised double-blind placebo-controlled trial among healthy postmenopausal Norwegian women, 1 year supplementation of vitamin K2 in the form of Natto capsules had no effect on bone loss rates.
Introduction
Japanese studies indicate that vitamin K2 (menaquinone-7 (MK-7)) intake may preserve bone strength, but this has not been documented in Europeans. The aim of this study was to assess the effect of MK-7 on bone mineral density (BMD) changes in postmenopausal Norwegian women.
Methods
Three hundred thirty-four healthy women between 50 and 60 years, 1–5 years after menopause, were recruited to a randomised double-blind placebo-controlled trial. The participants were randomly assigned into two groups, one …
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