Authors
Mohammad Reza Mohammadi, Seyed Ali Mostafavi, Seyed Ali Keshavarz, Mohammad Reza Eshraghian, Payam Hosseinzadeh, Mohammad Javad Hosseinzadeh-Attar, Seyed Mohammad Ali Kooshesh, Maryam Chamari, Shahin Akhondzadeh
Publication date
2012
Journal
Iranian journal of psychiatry
Volume
7
Issue
2
Pages
87
Publisher
Tehran University of Medical Sciences
Description
Objective
The aim of this study was to determine melatonin effects on sleep patterns, symptoms of hyperactivity and attention deficiency in children with attention-deficit hyperactivity disorder (ADHD).
Methods
Children with age range of 7-12 years who had a combined form of ADHD were randomly divided in to 2 groups according to gender blocks. One group took melatonin (3 or 6mg) combined with methylphenidate (Ritalin)(1mg/kg), and the other group took placebo combined with methylphenidate (1mg/kg). ADHD rating scale and sleep patterns questionnaires were completed. Research hypotheses were assessed at the baseline, the second, fourth and eighth weeks after the treatment.
Results
The mean sleep latency and total sleep disturbance scores were reduced in melatonin group, while the scores increased in the placebo group (p≥ 0.05). Data analysis, using ANOVA with repeated measures, did not show …
Scholar articles
MR Mohammadi, SA Mostafavi, SA Keshavarz… - Iranian journal of psychiatry, 2012