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The objective of this study was to evaluate the osteopromotive property of allogenic demineralized dentin matrix. There are different kinds of grafts and biomaterials being used for bone regeneration that are neither cost effective nor free of complications. Therefore, it would be ideal to utilize teeth that are extracted from other individuals (due to orthodontic treatments or wisdom teeth extractions, which are routinely discarded) to make an appropriate bone regenerative material, allogenic DDM. We hypothesized that allogenic DDM has bone regenerative properties. To test this hypothesis 30 New Zealand White rabbits were used. The rabbits were divided into four groups and sacrificed after 15, 30, 60, and 90 days. The thickness of bone specimens were measured before utilizing for micro‐CT. Blood samples were collected from all rabbits at each time point. Average bone thickness was increased by 54% in …