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Accurate assessment of anthropogenic carbon dioxide (CO₂) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere – the global carbon budget – is important to better understand the global carbon cycle, support the development of climate policies, and project future climate change. Here we describe data sets and methodology to quantify the five major components of the global carbon budget and their uncertainties. CO₂ emissions from fossil fuels and industry (E_FF) are based on energy statistics and cement production data, respectively, while emissions from land-use change (E_LUC), mainly deforestation, are based on land-cover change data and bookkeeping models. The global atmospheric CO₂ concentration is measured directly and its rate of growth (G_ATM) is computed from the annual changes in concentration. The ocean CO₂ sink (S_OCEAN) and terrestrial CO₂ sink (S_LAND) are estimated with global process models constrained by observations. The resulting carbon budget imbalance (B_IM), the difference between the estimated total emissions and the estimated changes in the atmosphere, ocean, and terrestrial biosphere, is a measure of imperfect data and understanding of the contemporary carbon cycle. All uncertainties are reported as ±1σ. For the last decade available (2007–2016), E_FF was 9.4 ± 0.5 GtC yr⁻¹, E_LUC 1.3 ± 0.7 GtC yr⁻¹, G_ATM 4.7 ± 0.1 GtC yr⁻¹, S_OCEAN 2.4 ± 0.5 GtC yr⁻¹, and S_LAND 3.0 ± 0.8 GtC yr⁻¹, with a budget imbalance B_IM of 0.6 GtC yr⁻¹ indicating overestimated emissions and/or underestimated sinks. For year 2016 alone, the growth in E_FF …