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Accurate assessment of anthropogenic carbon dioxide (CO₂) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere – the “global carbon budget” – is important to better understand the global carbon cycle, support the development of climate policies, and project future climate change. Here we describe data sets and methodology to quantify all major components of the global carbon budget, including their uncertainties, based on the combination of a range of data, algorithms, statistics, and model estimates and their interpretation by a broad scientific community. We discuss changes compared to previous estimates and consistency within and among components, alongside methodology and data limitations. CO₂ emissions from fossil fuels and industry (E_FF) are based on energy statistics and cement production data, respectively, while emissions from land-use change (E_LUC), mainly deforestation, are based on combined evidence from land-cover change data, fire activity associated with deforestation, and models. The global atmospheric CO₂ concentration is measured directly and its rate of growth (G_ATM) is computed from the annual changes in concentration. The mean ocean CO₂ sink (S_OCEAN) is based on observations from the 1990s, while the annual anomalies and trends are estimated with ocean models. The variability in S_OCEAN is evaluated with data products based on surveys of ocean CO₂ measurements. The global residual terrestrial CO₂ sink (S_LAND) is estimated by the difference of the other terms of the global carbon budget and compared to results of independent dynamic global …