Authors
Milad Allahgholi, Hossein Rahmani, Delaram Javdani, Zahra Sadeghi-Adl, Andreas Bender, Dezsö Módos, Gerhard Weiss
Publication date
2022/1/1
Journal
Intelligent Data Analysis
Volume
26
Issue
1
Pages
221-237
Publisher
IOS Press
Description
Analyzing the relationships among various drugs is an essential issue in the field of computational biology. Different kinds of informative knowledge, such as drug repurposing, can be extracted from drug-drug relationships. Scientific literature represents a rich source for the retrieval of knowledge about the relationships between biological concepts, mainly drug-drug, disease-disease, and drug-disease relationships. In this paper, we propose DDREL as a general-purpose method that applies deep learning on scientific literature to automatically extract the graph of syntactic and semantic relationships among drugs. DDREL remarkably outperforms the existing human drug network method and a random network respected to average similarities of drugs’ anatomical therapeutic chemical (ATC) codes. DDREL is able to shed light on the existing deficiency of the ATC codes in various drug groups. From the DDREL …
Total citations
20222023202412
Scholar articles
M Allahgholi, H Rahmani, D Javdani, Z Sadeghi-Adl… - Intelligent Data Analysis, 2022