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Durability is one of the most significant technical barriers to successful commercialization of polymer electrolyte membrane (PEM) fuel cells for practical vehicular applications. It is determined by the aging (degradation) and malfunction of various components during the long-term operation. Therefore, understanding the mechanisms of degradation modes in different components is crucial to the development of high-performing and long-lasting PEM fuel cells. In this review article, the critical degradation modes in major cell components, including membranes, catalyst layers, gas diffusion layers, and distribution plates, are comprehensively reviewed and analyzed, and the potential causes are described. Advanced experimental techniques to investigate the PEM fuel cell degradation modes reported in literature include steady-state durability tests and accelerated stress tests (ASTs). The steady-state durability test is …