Authors
David W Kimberlin, Jill Baley, Committee on Infectious Diseases, Committee on Fetus and Newborn, Michael T Brady, Carrie L Byington, H Dele Davies, Kathryn M Edwards, Mary P Glode, Mary Anne Jackson, Harry L Keyserling, Yvonne A Maldonado, Dennis L Murray, Walter A Orenstein, Gordon E Schutze, Rodney E Willoughby, Theoklis E Zaoutis, Lu-Ann Papile, Vinod K Bhutani, Waldemar A Carlo, James Cummings, Praveen Kumar, Richard A Polin, Rosemarie C Tan, Kasper S Wang, Kristi L Watterberg
Publication date
2013/2/1
Journal
Pediatrics
Volume
131
Issue
2
Pages
e635-e646
Publisher
American Academy of Pediatrics
Description
This Clinical Report was retired March 2022
Herpes simplex virus (HSV) infection of the neonate is uncommon, but genital herpes infections in adults are very common. Thus, although treating an infant with neonatal herpes is a relatively rare occurrence, managing infants potentially exposed to HSV at the time of delivery occurs more frequently. The risk of transmitting HSV to an infant during delivery is determined in part by the mother’s previous immunity to HSV. Women with primary genital HSV infections who are shedding HSV at delivery are 10 to 30 times more likely to transmit the virus to their newborn infants than are women with recurrent HSV infection who are shedding virus at delivery. With the availability of commercial serological tests that reliably can distinguish type-specific HSV antibodies, it is now possible to determine the type of maternal infection and, thus, further refine management of infants …
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Scholar articles
DW Kimberlin, J Baley… - Pediatrics, 2013