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In this paper we review the implications of neoclassical economic framings within the interdisciplinary field of land-change science. We argue that current pressing global environmental problems, such as land grabs, loss of critical carbon sinks and the increasing importance of corporate actors in land-use decision-making, necessitate a reconsideration of neoclassical conceptualizations of what the economy is, who economic actors are and how they make decisions, and how environment–economy linkages operate in a globalized world. We argue that concepts from economic geography can help land change science move beyond neoclassical framings. The first concept is that the economic (including markets, commodities, and rational decision-makers) is neither separate nor universal, but is historical and socially embedded. The second is to use these notions to understand the spatial organization of economic …