Authors
Judy Garber, Gregory N Clarke, V Robin Weersing, William R Beardslee, David A Brent, Tracy RG Gladstone, Lynn L DeBar, Frances L Lynch, Eugene D’Angelo, Steven D Hollon, Wael Shamseddeen, Satish Iyengar
Publication date
2009/6/3
Journal
Jama
Volume
301
Issue
21
Pages
2215-2224
Publisher
American Medical Association
Description
Context
Adolescent offspring of depressed parents are at markedly increased risk of developing depressive disorders. Although some smaller targeted prevention trials have found that depression risk can be reduced, these results have yet to be replicated and extended to large-scale, at-risk populations in different settings.
Objective
To determine the effects of a group cognitive behavioral (CB) prevention program compared with usual care in preventing the onset of depression.
Design, Setting, and Participants
A multicenter randomized controlled trial conducted in 4 US cities in which 316 adolescent (aged 13-17 years) offspring of parents with current or prior depressive disorders were recruited from August 2003 through February 2006. Adolescents had a past history of depression, current elevated but subdiagnostic depressive symptoms, or both. Assessments were conducted at baseline, after the 8-week …
Total citations
Scholar articles
J Garber, GN Clarke, VR Weersing, WR Beardslee… - Jama, 2009