Authors
Cochrane Gut Group, Alaa Rostom, Catherine Dube, George A Wells, Peter Tugwell, Vivian Welch, Emilie Jolicoeur, Jessie McGowan, Angel Lanas, Eleanor Rushton, Tushar Shukla
Publication date
1996/9/1
Source
Cochrane database of systematic reviews
Volume
2021
Issue
10
Publisher
John Wiley & Sons, Ltd
Description
Background
Non‐steroidal anti‐inflammatory drugs (NSAIDs) are important agents in the management of arthritic and inflammatory conditions, and are among the most frequently prescribed medications in North America and Europe. However, there is overwhelming evidence linking these agents to a variety of gastrointestinal (GI) toxicities.
Objectives
To review the effectiveness of common interventions for the prevention of NSAID induced upper GI toxicity.
Search methods
We searched MEDLINE from 1966 to May 2009, Current Contents for six months prior to May 2009, EMBASE to May 2009, and the Cochrane Controlled Trials Register from 1973 to May 2009. Recent conference proceedings were reviewed and content experts and companies were contacted.
Selection criteria
Randomized controlled clinical trials (RCTs) of prostaglandin analogues (PA), H2‐receptor antagonists (H2RA) or proton pump …
Total citations
Scholar articles
Cochrane Gut Group, A Rostom, C Dube, GA Wells… - Cochrane database of systematic reviews, 1996
A Rostom, G Wells, P Tugwell - ACP JOURNAL CLUB, 2001