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Medical devices measure vital parameters such as pulse, respiration rate, and blood oxygenation, over periods of days or weeks in a continuous manner. Traditional systems only support such requirements in stationary applications where a constant power supply is available. Trends toward remote healthcare and telemedicine require wearable devices, able to provide similar functionalities in wireless mode. Miniaturized and thin form factors, desirable in wearable applications, set stringent constraints on the available power, and consequently on the accuracy and lifetime. Energy harvesting combined with low-power design and energy efficient processing can significantly extend the lifetime of wearable devices. This paper presents a wearable pulse oximeter assembled in a 3D ring-like geometry that achieves self-sustainability by exploiting efficient power management, solar energy harvesting, and ultra-low …