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Recently, an extended operator of fractional derivative related to a generalized Beta function was used in order to obtain some generating relations involving the extended hypergeometric functions . The main object of this paper is to present a further generalization of the extended fractional derivative operator and apply the generalized extended fractional derivative operator to derive linear and bilinear generating relations for the generalized extended Gauss, Appell and Lauricella hypergeometric functions in one, two and more variables. Some other properties and relationships involving the Mellin transforms and the generalized extended fractional derivative operator are also given.