Authors
Richard Layte, Cathal McCrory, Cliona Ni Cheallaigh, Nollaig Bourke, Mika Kivimaki, Ana Isabel Ribeiro, Silvia Stringhini, Paolo Vineis
Publication date
2019/1/28
Journal
Scientific reports
Volume
9
Issue
1
Pages
796
Publisher
Nature Publishing Group UK
Description
The status anxiety hypothesis proposes that systematic inflammation as a consequence of chronic psycho-social stress is a possible pathway linking socio-economic position (SEP) to premature ageing and is a possible explanation for cross-national variation in patterns of health and well-being. Harmonised data from the LIFEPATH consortium on 18,349 individuals aged 50 to 75 and 30,632 observations are used to measure variation in the association between inflammation measured as C-reactive protein and SEP across four countries (Britain, Ireland, Portugal and Switzerland) and five studies (ELSA, Whitehall II, TILDA, EPIPorto and SKIPOGH). Adjusting for population composition, mean concentrations of CRP are highest in Portugal, the country with the highest income inequality and lowest in Switzerland, a lower income inequality country. Across all of the studies, lower SEP groups have higher mean …
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