Authors
Cheryl L Grady, Mellanie V Springer, Donaya Hongwanishkul, Anthony R McIntosh, Gordon Winocur
Publication date
2006/2/1
Journal
Journal of cognitive neuroscience
Volume
18
Issue
2
Pages
227-241
Publisher
MIT Press
Description
A number of theories have emerged to explain the well-studied changes in memory that occur with age. Many of these theories invoke mechanisms that have the potential to affect multiple cognitive domains, in addition to memory. Such mechanisms include alterations in attentional or inhibitory function, or dysfunction of specific brain areas, such as the frontal lobes. To gain insight into these mechanisms, we used functional magnetic resonance imaging to examine brain activity during encoding and recognition tasks in young, middle-aged, and older adults to identify correlations between age and brain activity across the various tasks. The goal was to see whether these correlations were task-specific or common across tasks, and to determine whether age differences emerged in a linear fashion over the adult years. Across all memory tasks, at both encoding and recognition, linear increases of activity with age were …
Total citations
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Scholar articles
CL Grady, MV Springer, D Hongwanishkul… - Journal of cognitive neuroscience, 2006