Authors
Manisha Brahmachary, SPT Krishnan, Judice L. Y. Koh, Asif M. Khan, Seng Hong Seah, Tin Wee Tan, Vladimir Brusic, Vladimir B. Bajic
Publication date
2004/1/1
Journal
Nucleic acids research
Volume
32
Issue
suppl_1
Pages
D586-D589
Publisher
Oxford University Press
Description
Antimicrobial peptides (AMPs) are important components of the innate immune system of many species. These peptides are found in eukaryotes, including mammals, amphibians, insects and plants, as well as in prokaryotes. Other than having pathogen‐lytic properties, these peptides have other activities like antitumor activity, mitogen activity, or they may act as signaling molecules. Their short length, fast and efficient action against microbes and low toxicity to mammals have made them potential candidates as peptide drugs. In many cases they are effective against pathogens that are resistant to conventional antibiotics. They can serve as natural templates for the design of novel antimicrobial drugs. Although there are vast amounts of data on natural AMPs, they are not available through one central resource. We have developed a comprehensive database (ANTIMIC, http://research.i2r. a‐star.edu.sg/Templar/DB …
Total citations
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Scholar articles
M Brahmachary, SPT Krishnan, JLY Koh, AM Khan… - Nucleic acids research, 2004