Authors
Matteo Pagnesi, Oscar Alberto Gomez Vilamajó, Alejandro Meiriño, Carlos Alberto Dumont, Alexandre Mebazaa, Beth Davison, Marianna Adamo, Mattia Arrigo, Marianela Barros, Jan Biegus, Jelena Celutkiene, Kamilė Čerlinskaitė‐Bajorė, Ovidiu Chioncel, Alain Cohen‐Solal, Albertino Damasceno, Rafael Diaz, Christopher Edwards, Gerasimos Filippatos, Etienne Gayat, Antoine Kimmoun, Carolyn SP Lam, Maria Novosadova, Peter S Pang, Piotr Ponikowski, Hadiza Saidu, Karen Sliwa, Koji Takagi, Jozine M Ter Maaten, Daniela Tomasoni, Adriaan A Voors, Gad Cotter, Marco Metra
Publication date
2024/3
Journal
European Journal of Heart Failure
Volume
26
Issue
3
Pages
638-651
Publisher
John Wiley & Sons, Ltd.
Description
Aims
A high‐intensity care (HIC) strategy with rapid guideline‐directed medical therapy (GDMT) up‐titration and close follow‐up visits improved outcomes, compared to usual care (UC), in patients recently hospitalized for acute heart failure (AHF). Hypotension is a major limitation to GDMT implementation. We aimed to assess the impact of baseline systolic blood pressure (SBP) on the effects of HIC versus UC and the role of early SBP changes in STRONG‐HF.
Methods and results
A total of 1075 patients hospitalized for AHF with SBP ≥100 mmHg were included in STRONG‐HF. For the purpose of this post‐hoc analysis, patients were stratified by tertiles of baseline SBP (<118, 118–128, and ≥129 mmHg) and, in the HIC arm, by tertiles of changes in SBP from the values measured before discharge to those measured at 1 week after discharge (≥2 mmHg increase, ≤7 mmHg decrease to <2 mmHg …
Total citations
20242
Scholar articles
M Pagnesi, OAG Vilamajó, A Meiriño, CA Dumont… - European Journal of Heart Failure, 2024