Authors
Veronica Guidetti, Giovanni Dolci, Erica Franceschini, Erica Bacca, Giulia Jole Burastero, Davide Ferrari, Valentina Serra, Fabrizio Di Benedetto, Cristina Mussini, Federica Mandreoli
Publication date
2023/10/9
Conference
2023 IEEE 10th International Conference on Data Science and Advanced Analytics (DSAA)
Pages
1-10
Publisher
IEEE
Description
This study introduces a novel approach to mine risk factors for short-term death after liver transplantation (LT). The method outputs intelligible survival models by combining Cox’s regression with a genetic programming technique known as multi-objective symbolic regression (MOSR). We consider 485 Electronic Health Records (EHRs) of patients who underwent LT, containing information on hospitalization and preoperative conditions, with a focus on infections and colonizations by multi-resistant Gram-negative bacteria. We evaluate MOSR outcomes against several performance metrics and demonstrate that they are well-calibrated, predictive, safe, and parsimonious. Finally, we select the most promising post-LT early survival risk score based on information criteria, performance, and out-of-distribution safety. Validating this technique at a multicenter level could improve service pipeline logistics through a …
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Scholar articles
V Guidetti, G Dolci, E Franceschini, E Bacca… - 2023 IEEE 10th International Conference on Data …, 2023