Authors
C Barr Taylor, Marston E Youngblood, Diane Catellier, Richard C Veith, Robert M Carney, Matthew M Burg, Peter G Kaufmann, John Shuster, Thomas Mellman, James A Blumenthal, Ranga Krishnan, Allan S Jaffe, ENRICHD Investigators
Publication date
2005/7/1
Journal
Archives of general psychiatry
Volume
62
Issue
7
Pages
792-798
Publisher
American Medical Association
Description
Background
Depression after myocardial infarction (MI) is associated with higher morbidity and mortality. Although antidepressants are effective in reducing depression, their use in patients with cardiovascular disease remains controversial.
Objective
To undertake a secondary analysis to determine the effects of using antidepressants on morbidity and mortality in post-MI patients who participated in the Enhancing Recovery in Coronary Heart Disease study.
Design
Observational secondary analysis.
Setting
Eight academic sites.
Patients
The Enhancing Recovery in Coronary Heart Disease clinical trial randomized 2481 depressed and/or socially isolated patients from October 1, 1996, to October 31, 1999. Depression was diagnosed using a structured clinical interview. This analysis was conducted on the 1834 patients enrolled with depression (849 women and 985 men).
Intervention
Use of antidepressant medication …
Total citations
Scholar articles
CB Taylor, ME Youngblood, D Catellier, RC Veith… - Archives of general psychiatry, 2005