Authors
Anthony R Otley, Anne M Griffiths, Sandra Hale, Subra Kugathasan, Marian Pfefferkorn, Adam Mezoff, Joel Rosh, Vasundhara Tolia, James Markowitz, David Mack, Maria Oliva-Hemker, Robert Wyllie, Robert Rothbaum, Athos Bousvaros, Fernando J Del Rosario, Jonathan Evans, Wade Blanchard, Jeffrey Hyams
Publication date
2006/8/1
Journal
Inflammatory bowel diseases
Volume
12
Issue
8
Pages
684-691
Publisher
Oxford University Press
Description
Background and Aims
Assessment of health-related quality of life (HRQOL) is of increasing importance in the evaluation of new therapies for inflammatory bowel disease (IBD). Available data concerning HRQOL in pediatric patients are sparse and uniformly cross-sectional. The aim of this study was to describe HRQOL and influential factors in newly diagnosed pediatric patients with Crohn's disease and ulcerative colitis during the first 12 months after diagnosis.
Materials and Methods
Participants were drawn from a large, prospectively derived observational IBD registry of pediatric patients studied through 18 U.S. and Canadian centers. Patients who had completed a baseline IMPACT questionnaire and for whom there were 12 months of follow-up data available were included. In addition to description of cohort, factors that were believed to influence HLQOL were assessed during …
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Scholar articles
AR Otley, AM Griffiths, S Hale, S Kugathasan… - Inflammatory bowel diseases, 2006