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Usability is considered to be one of the most important quality factors that determine the success or failure of an interactive system. This can be explained by the ever-increasing number of studies addressing the integration of the usability evaluation at the development process. However, most of these proposals aim to guide the user interface transformation process according to a set of usability criteria allowing the generation of user interfaces which meet the usability requirement. In fact, the selection of the adequate alternative transformation depends on the usability attributes that will be met. This paper proposed an approach that considers the user interface generation process as a usability optimization problem according to given usability optimization objectives. The aims to generate all possible concrete user interfaces from a given abstract user interface. Then, the usability optimization process selects the optimal concrete user interface for a specific context of use.