Authors
Magdalena Nowakowska, Salwa S Zghebi, Darren M Ashcroft, Iain Buchan, Carolyn Chew-Graham, Tim Holt, Christian Mallen, Harm Van Marwijk, Niels Peek, Rafael Perera-Salazar, David Reeves, Martin K Rutter, Stephen F Weng, Nadeem Qureshi, Mamas A Mamas, Evangelos Kontopantelis
Publication date
2019/12
Journal
BMC medicine
Volume
17
Pages
1-10
Publisher
BioMed Central
Description
Background
The presence of additional chronic conditions has a significant impact on the treatment and management of type 2 diabetes (T2DM). Little is known about the patterns of comorbidities in this population. The aims of this study are to quantify comorbidity patterns in people with T2DM, to estimate the prevalence of six chronic conditions in 2027 and to identify clusters of similar conditions.
Methods
We used the Clinical Practice Research Datalink (CPRD) linked with the Index of Multiple Deprivation (IMD) data to identify patients diagnosed with T2DM between 2007 and 2017. 102,394 people met the study inclusion criteria. We calculated the crude and age-standardised prevalence of 18 chronic conditions present at and after the T2DM diagnosis. We analysed longitudinally the 6 most common conditions and forecasted their prevalence in 2027 using linear regression. We used agglomerative hierarchical …
Scholar articles
M Nowakowska, SS Zghebi, DM Ashcroft, I Buchan… - BMC medicine, 2019