Authors
Hany S Abed, Gary A Wittert, Darryl P Leong, Masoumeh G Shirazi, Bobak Bahrami, Melissa E Middeldorp, Michelle F Lorimer, Dennis H Lau, Nicholas A Antic, Anthony G Brooks, Walter P Abhayaratna, Jonathan M Kalman, Prashanthan Sanders
Publication date
2013/11/20
Journal
Jama
Volume
310
Issue
19
Pages
2050-2060
Publisher
American Medical Association
Description
Importance
Obesity is a risk factor for atrial fibrillation. Whether weight reduction and cardiometabolic risk factor management can reduce the burden of atrial fibrillation is not known.
Objective
To determine the effect of weight reduction and management of cardiometabolic risk factors on atrial fibrillation burden and cardiac structure.
Design, Setting, and Patients
Single-center, partially blinded, randomized controlled study conducted between June 2010 and December 2011 in Adelaide, Australia, among overweight and obese ambulatory patients (N = 150) with symptomatic atrial fibrillation. Patients underwent a median of 15 months of follow-up.
Interventions
Patients were randomized to weight management (intervention) or general lifestyle advice (control). Both groups underwent intensive management of cardiometabolic risk factors.
Main Outcomes and Measures
The primary outcomes were Atrial Fibrillation …
Scholar articles
HS Abed, GA Wittert, DP Leong, MG Shirazi, B Bahrami… - Jama, 2013