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These guidelines were developed by the Atzelsberg Research Group of the IAH (http://www. hyperthermie. org) of the German Cancer Society (“Deutsche Krebs gesellschaft”) to specifically ensure that the multi-institutional studies initiated by the Atzelsberg Research Group are executed following a single, uniform level of quality. They are recognized by the European Society for Hyperthermic Oncology (ESHO) and as such serve as the current (pre) standard to ensure that the application and registration of the deep hyperthermia treatment is according current knowledge and experience both from technological and clinical considerations. ESHO notes that to enhance uniformity of quality in hyperthermia application at an international level, a commitment exists with their sister hyperthermia organization in the USA (STM) to design quality assurance guidelines valid for all types of hyperthermia and recognized by both STM and ESHO.