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Foxtail millet (Setaria italica L.) is a small millet predominantly cultivated in arid and semi-arid regions of the world. India is the second-largest producer of foxtail millet, next to China, and the crop has importance in the history and civilization of the human race in these two countries. Although the foxtail millet was widely cultivated in the ancient era, it has lost its importance with time and became a marginally grown crop catering to the nutritional requirements of a limited population. Despite this, the crop has excellent yield contributing to agronomic traits along with climate-resilient characteristics. Being a C₄ panicoid species with a small diploid genome, short lifecycle, in-breeding nature, and close relationship with biofuel grasses, foxtail millet has recently been considered as a C₄ model crop to understand several agronomically important traits, including stress tolerance. Given the importance, the genome sequence …