Authors
David Martin, Héloïse Smet, Ana Cristina Da Silva Costa, Nermin Halkic, Emilie Uldry, Parissa Tabrizian, Myron Schwartz, Ahmad Mahamid, Claire Goumard, Olivier Scatton, Julie Perinel, Mustapha Adham, Nicolas Demartines, Emmanuel Melloul
Publication date
2023/7/1
Journal
HPB
Volume
25
Issue
7
Pages
836-844
Publisher
Elsevier
Description
Background
According to the Barcelona Clinic Liver Cancer (BCLC) staging system, liver resection (LR) is recommended for early-stage (BCLC-A) hepatocellular carcinoma (HCC) but not for intermediate-stage (BCLC-B). This study aimed to assess the outcomes of LR in these patients using a subclassification tumour burden score (TBS).
Methods
All consecutive patients that underwent LR for BCLC-A and BCLC-B HCC between 01/2010 and 12/2020 in 4 tertiary referral centers were included. Clinical outcomes and overall survival (OS) were assessed in relation to TBS and BCLC stages.
Results
Among 612 patients included, 562 were classified as BCLC-A and 50 as BCLC-B. The incidence of overall postoperative complications (56.0 vs 41.5%, p = 0.053) and mortality (0 vs 1.6%, p = 1.000) were similar between BCLC-A and BCLC-B patients. OS was significantly higher for BCLC A/low TBS than BCLC B/low TBS …
Total citations
Scholar articles
D Martin, H Smet, ACDS Costa, N Halkic, E Uldry… - HPB, 2023