Authors
Nicolas Boussekey, Arnaud Chiche, Karine Faure, Patrick Devos, Benoit Guery, Thibaud d’Escrivan, Hugues Georges, Olivier Leroy
Publication date
2008/9
Journal
Intensive care medicine
Volume
34
Pages
1646-1653
Publisher
Springer-Verlag
Description
Objective
High volume hemofiltration (HVHF) has shown potential benefits in septic animals and a few reports suggested a hemodynamic improvement in humans. However, randomized studies are still lacking. Our goal was to evaluate the hemodynamic effects of HVHF in septic shock patients with acute renal failure (ARF).
Design and setting
Prospective randomized study in an intensive care unit (ICU).
Patients
Twenty patients with septic shock and ARF.
Interventions
Patients were randomized to either high volume hemofiltration [HVHF 65 ml/(kg h)] or low volume hemofiltration [LVHF 35 ml/(kg h). Vasopressor dose was adjusted to reach a mean arterial pressure (MAP) > 65 mmHg.
Measurements and results
We performed six hourly measurements …
Total citations
Scholar articles
N Boussekey, A Chiche, K Faure, P Devos, B Guery… - Intensive care medicine, 2008