Authors
Leonardo A Frizon, Olivia Hogue, Rebecca Achey, Darlene P Floden, Sean Nagel, Andre G Machado, Darlene A Lobel
Publication date
2019/9/1
Journal
Neurosurgery
Volume
85
Issue
3
Pages
343-349
Publisher
LWW
Description
BACKGROUND
There is a growing attention to determine the factors that predict quality of life (QoL) improvement after deep brain stimulation (DBS) for Parkinson's disease. Prior literature has largely focused on examining predictors one at a time, sometimes controlling for covariates.
OBJECTIVE
To develop a model that could be used as a nomogram to predict improvement in QoL following DBS surgery in patients with Parkinson's disease.
METHODS
All patients with complete pre-and postoperative movement disorder and neuropsychological testing who underwent DBS at a single institution between 2007-2012 were analyzed. The Parkinson's Disease Questionnaire-39 (PDQ-39) was used to measure QoL. Potential predictive factors, including patient demographics, clinical presentation characteristics, radiographic imaging, and motor and psychological testing were analyzed for impact on QoL.
RESULTS
Sixty …
Scholar articles
LA Frizon, O Hogue, R Achey, DP Floden, S Nagel… - Neurosurgery, 2019