Authors
Hesham Abboud, Darlene Floden, Nicolas R Thompson, Gencer Genc, Srivadee Oravivattanakul, Faisal Alsallom, Bengwei Swa, Cynthia Kubu, Mayur Pandya, Michal Gostkowski, Scott Cooper, Andre G Machado, Hubert H Fernandez
Publication date
2015/3/1
Journal
Parkinsonism & related disorders
Volume
21
Issue
3
Pages
249-253
Publisher
Elsevier
Description
Introduction
Unlike dementia, the effect of mild cognitive impairment (MCI) on outcomes after deep brain stimulation (DBS) in Parkinson's disease (PD) is less clear. We aimed to examine the effect of MCI on short- and long-term DBS outcomes.
Methods
To study the effect of MCI type, cognitive domains (attention, language, visuospatial, memory, executive function), and Dementia Rating Scale (DRS) score on immediate postoperative outcomes (postoperative confusion, hospitalization days), PD patients who underwent DBS at our Center from 2006 to 2011 were analyzed. To determine cognitive predictors of intermediate (6-month) and long-term (1-year) post-operative outcomes, the changes in functional and quality-of-life (QOL) scores were analyzed in a smaller group with available preoperative health status measures.
Results
We identified 130 patients [71% male, mean age: 63 ± 9.1, mean PD duration: 10.7 ± 5.1 …
Scholar articles
H Abboud, D Floden, NR Thompson, G Genc… - Parkinsonism & related disorders, 2015