Authors
Robyn M Busch, Darlene P Floden, Brigid Prayson, Jessica S Chapin, Kevin H Kim, Lisa Ferguson, William Bingaman, Imad M Najm
Publication date
2016/11/29
Journal
Neurology
Volume
87
Issue
22
Pages
2363-2369
Publisher
Lippincott Williams & Wilkins
Description
Objective
This retrospective, observational study examined the frequency and magnitude of change in naming ability as a function of side/site of epilepsy surgery and identified predictive factors to assist clinicians in identifying patients at low, moderate, or high risk of postoperative naming decline.
Methods
A total of 875 adults with pharmacoresistant epilepsy (454 left/421 right; 763 temporal/87 frontal/25 posterior quadrant) met inclusion criteria and completed the Boston Naming Test before and after surgery. Clinically meaningful change in naming ability was assessed using reliable change indices for epilepsy. Demographic, cognitive, and seizure variables were examined to determine factors most predictive of naming decline and to develop a decision tree to assist with clinical decision-making.
Results
Naming decline was rare in right-sided resections and did not exceed the level expected by chance (5% overall …
Scholar articles
RM Busch, DP Floden, B Prayson, JS Chapin, KH Kim… - Neurology, 2016