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Plasma and urine were collected over a 24 h period after the consumption by humans of 200 g of strawberries, containing 222 µmol of pelargonidin-3-O-glucoside, with and without cream. The main metabolite, a pelargonidin-O-glucuronide, reached a peak plasma concentration (C_max) of 274 ± 24 nmol/L after 1.1 ± 0.4 h (t_max) when only strawberries were ingested. When the strawberries were eaten with cream, the C_max was not statistically different but the t_max at 2.4 ± 0.5 h was delayed significantly (p < 0.001). The pelargonidin-O-glucuronide, along with smaller quantities of other metabolites, was also excreted in urine in quantities corresponding to ca. 1% of anthocyanin intake. The quantities excreted over the 0–24 h collection period were not influenced significantly by cream. However, the 0–2 h excretion of anthocyanin metabolites was significantly lower when the strawberries were eaten with cream …