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With the development and advancement of information communication technology, smart wearable devices are playing a more and more important role in peoples’ daily lives. This study aims to investigate the adoption of smart wearable devices to assist healthcare in China. Based on the previous technology diffusion theories (e.g., TAM, IDT), a research model with ten research hypotheses was proposed in this research. The research model was empirically tested with a sample of 180 users of smart wearable devices in China. The results indicated that seven of the ten research hypotheses were significantly supported. The most significant determinant for users’ attitude towards smart wearable devices was trust. However, personal characteristics did not have a significant positive impact on both users’ attitude and behavior intention to use smart wearable devices.