Authors
Mirjam Severs, Lieke M Spekhorst, Marie-Josée J Mangen, Gerard Dijkstra, Mark Löwenberg, Frank Hoentjen, Andrea E van der Meulen-de Jong, Marieke Pierik, Cyriel Y Ponsioen, Gerd Bouma, Janneke C Van Der Woude, Mirthe E van der Valk, Marielle JL Romberg-Camps, Cees HM Clemens, Paul van de Meeberg, Nofel Mahmmod, Jeroen Jansen, Bindia Jharap, Rinse K Weersma, Bas Oldenburg, Eleonora AM Festen, Herma H Fidder
Publication date
2018/5/18
Journal
Inflammatory bowel diseases
Volume
24
Issue
6
Pages
1298-1306
Publisher
Oxford University Press
Description
Background
The understanding of gender differences in inflammatory bowel disease (IBD) patients is an important step towards tailored treatment for the individual patient. The aim of this study was to compare disease phenotype, clinical manifestations, disease activity, and healthcare utilization between men and women with Crohn’s disease (CD) and ulcerative colitis (UC).
Methods
Two multicenter observational cohort studies with a prospective design were used to explore the differences between men and women regarding demographic and phenotypic characteristics and healthcare utilization. Detailed data on IBD-phenotype was mainly available from the Dutch IBD Biobank, while the COIN cohort provided healthcare utilization data.
Results
In the Dutch IBD Biobank study, 2118 CD patients and 1269 UC patients were analyzed. Female CD patients …
Scholar articles
M Severs, LM Spekhorst, MJJ Mangen, G Dijkstra… - Inflammatory bowel diseases, 2018