Authors
Bertrand Janne d’Othée, Uwe Siebert, Ricardo Cury, Hossein Jadvar, Edward J Dunn, Udo Hoffmann
Publication date
2008/3/1
Source
European Journal of Radiology
Volume
65
Issue
3
Pages
449-461
Publisher
Elsevier
Description
OBJECTIVES
Systematic review of diagnostic accuracy of contrast enhanced coronary computed tomography (CE-CCT).
BACKGROUND
Noninvasive detection of coronary artery stenosis (CAS) by CE-CCT as an alternative to catheter-based coronary angiography (CCA) may improve patient management.
METHODS
Forty-one articles published between 1997 and 2006 were included that evaluated native coronary arteries for significant stenosis and used CE-CCT as diagnostic test and CCA as reference standard. Study group characteristics, study methodology and diagnostic outcomes were extracted. Pooled summary sensitivity and specificity of CE-CCT were calculated using a random effects model (1) for all coronary segments, (2) assessable segments, and (3) per patient.
RESULTS
The 41 studies totaled 2515 patients (75% males; mean age: 59 years, CAS prevalence: 59%). Analysis of all coronary …
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Scholar articles
BJ d'Othée, U Siebert, R Cury, H Jadvar, EJ Dunn… - European Journal of Radiology, 2008