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River basin rainfall series and extensive river flow records are used to characterize and improve understanding of spatial and temporal variability in sub-Saharan African water resources during the last century. Nine major international river basins were chosen for examination primarily for their extensive, good quality flow records. A range of statistical descriptors highlight the substantial variability in rainfall and river flows [eg, differences in rainfall (flows) of up to− 14%(− 51%) between 1931–60 and 1961–90 in West Africa], the marked regional differences, and the modest intraregional differences. On decadal time scales, sub-Saharan Africa exhibits drying across the Sahel after the early 1970s, relative stability punctuated by extreme wet years in East Africa, and periodic behavior underlying high interannual variability in southern Africa. Central Africa shows very modest decadal variability, with some similarities to …