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Predictive process monitoring is a family of techniques to analyze events produced during the execution of a business process in order to predict the future state or the final outcome of running process instances. Existing techniques in this field are able to predict, at each step of a process instance, the likelihood that it will lead to an undesired outcome. These techniques, however, focus on generating predictions and do not prescribe when and how process workers should intervene to decrease the cost of undesired outcomes. This paper proposes a framework for prescriptive process monitoring, which extends predictive monitoring with the ability to generate alarms that trigger interventions to prevent an undesired outcome or mitigate its effect. The framework incorporates a parameterized cost model to assess the cost–benefit trade-off of generating alarms. We show how to optimize the generation of alarms given an …