Authors
Amit J Shah, Emir Veledar, Yuling Hong, J Douglas Bremner, Viola Vaccarino
Publication date
2011/11/7
Journal
Archives of general psychiatry
Volume
68
Issue
11
Pages
1135-1142
Publisher
American Medical Association
Description
Context
Although depression is associated with increased cardiovascular morbidity and mortality, there is virtually no information on whether it also increases the risk in young populations.
Objectives
We sought to determine the association of unipolar and bipolar depression and a history of attempted suicide with mortality due to ischemic heart disease (IHD) and cardiovascular disease (CVD) in young US adults and to examine potential sex differences.
Design
Longitudinal epidemiologic study.
Setting
Nationally representative sample of US adults.
Participants
A total of 7641 US adults aged 17 to 39 years from the 1988-1994 Third National Health and Nutrition Examination Survey.
Main Outcome Measures
Cardiovascular disease and IHD mortality. Unipolar/bipolar depression and a history of attempted suicide were assessed via the Diagnostic Interview Schedule.
Results
After a median follow-up of 14.9 years, a total of …
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