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Analyzing protein interactions and protein functions is crucial for the analysis of complex biological processes as well as the consequences from aberrant gene products [1]. Protein-Protein Interaction Networks (PPIN) are invaluable means enabling scientists to get a global understanding of interactomes, while analyzing individual protein functions [2]. High-throughput experiments and complete literature mining analyses have been used to deliver well-structured data into scientific databases reporting on proteins, their interactions and functions. These repositories form a precious resource to scientists, but only cover a portion of the proteome and often underrepresented alternative splice forms [3]. Alternative splicing (AS) is a cellular process that produces from a single gene different physical variants of a given protein which may differ in its structure or its function. This process produces molecular variability and …