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A new wave of the IT revolution, e-government, presents a tremendous opportunity to move forward providing higher quality, and cost-effective government services as well as creating a better relationship between citizens and government. The literature review, presented in this paper however, indicated that e-government readiness is a major concern, and that currently there is little availability of comprehensive assessment methods for e-government readiness and most of the assessment frameworks, reviewed for this study, are varied in terms of philosophies, objectives, methodologies, approaches, and results. To this end, this research aims to develop a comprehensive framework of associated guidelines and tools to support E-government Information Systems (EGIS) readiness, with a specific focus on the EGIS migration to the Cloud Computing provisioning model.