Authors
Ghassan S Kassab, YC Fung
Publication date
1994/7/1
Journal
American Journal of Physiology-Heart and Circulatory Physiology
Volume
267
Issue
1
Pages
H319-H325
Description
To provide a morphometric basis for any mathematical modeling of the coronary vasculature, data on the network of coronary capillary blood vessels and the topology of the arteriolar supply and venular drainage relative to the capillaries are presented. The diameters, lengths, and branching patterns of the coronary capillary blood vessels in the right and left ventricles of four pigs were measured. The locations of the coronary arterioles and venules were identified, topological maps were constructed, and the mean functional length of capillaries connecting an arteriole to an adjacent venule was measured. The vasculature was fixed by perfusing the coronary vessels with a catalyzed polymer. After the polymer hardened, plugs of the myocardium were removed, sectioned, dehydrated, and cleared to render the capillary network visible in a light microscope. The capillaries then were traced by optical sectioning. We …
Total citations
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Scholar articles
GS Kassab, YC Fung - American Journal of Physiology-Heart and Circulatory …, 1994