Authors
Jennifer Glaus, Roland von Känel, Aurélie M Lasserre, Marie‐Pierre F Strippoli, Caroline L Vandeleur, Enrique Castelao, Mehdi Gholam‐Rezaee, Ciro Marangoni, En‐Young N Wagner, Pedro Marques‐Vidal, Gérard Waeber, Peter Vollenweider, Martin Preisig, Kathleen R Merikangas
Publication date
2018/4
Journal
Depression and anxiety
Volume
35
Issue
4
Pages
360-371
Description
Background
Although there has been abundant research on chronic low‐grade inflammation as a potential mechanism underlying the link between mood disorders and cardiovascular risk, less is known about the role of inflammatory factors and anxiety disorders. The aim of this paper is to evaluate the bi‐directional associations between inflammatory markers including interleukin (IL)‐6, tumor necrosis factor (TNF)‐α, and high sensitivity C‐reactive protein (hsCRP) with anxiety disorders and its subgroups.
Methods
The sample consisted of 3,113 participants (53.7% women; mean age: 51.0, S.D. 8.8 years), randomly selected from the general population, who underwent comprehensive somatic and psychiatric evaluations at baseline and follow‐up (mean follow‐up duration = 5.5 years, S.D. 0.6). Anxiety disorders were assessed with semistructured diagnostic interviews. Inflammatory biomarkers were analyzed in …
Scholar articles
J Glaus, R von Känel, AM Lasserre, MPF Strippoli… - Depression and anxiety, 2018