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Securing critical systems such as Cyber-Physical Systems (CPS) is an important feature especially when it comes to critical transmitted data in a real-time environment. At the same time, the implementation of security counter-measures in such systems may impact transmission delays of critical tasks. For this reason selecting proper security mechanisms in such critical systems is an important issue. In this context, we propose a model-based approach for selecting proper security solution alternatives composed of security patterns at early design stage against real-time requirements. We provide a generalizable and tool-supported solution to support the approach using UML and its profiles. A validation of the work is presented via a simplified version of SCADA (Supervisory Control and Data Acquisition) system case study.