Authors
John P Pierce, Marcia L Stefanick, Shirley W Flatt, Loki Natarajan, Barbara Sternfeld, Lisa Madlensky, Wael K Al-Delaimy, Cynthia A Thomson, Sheila Kealey, Richard Hajek, Barbara A Parker, Vicky A Newman, Bette Caan, Cheryl L Rock
Publication date
2007/6/10
Journal
Journal of Clinical Oncology
Volume
25
Issue
17
Pages
2345-2351
Publisher
American Society of Clinical Oncology
Description
Purpose
Single-variable analyses have associated physical activity, diet, and obesity with survival after breast cancer. This report investigates interactions among these variables.
Patients and Methods
A prospective study was performed of 1,490 women diagnosed and treated for early-stage breast cancer between 1991 and 2000. Enrollment was an average of 2 years postdiagnosis. Only seven women were lost to follow-up through December 2005.
Results
In univariate analysis, reduced mortality was weakly associated with higher vegetable-fruit consumption, increased physical activity, and a body mass index that was neither low weight nor obese. In a multivariate Cox model, only the combination of consuming five or more daily servings of vegetables-fruits, and accumulating 540+ metabolic equivalent tasks-min/wk (equivalent to walking 30 minutes 6 d/wk), was …
Total citations
Scholar articles
JP Pierce, ML Stefanick, SW Flatt, L Natarajan… - Journal of Clinical Oncology, 2007