Authors
AM Vazquez, M Alfonso, B Lanne, K-A Karlsson, A Carr, O Barroso, LE Fernández, E Rengifo, ME Lanio, C Alvarez, J Zeuthen, R Pérez
Publication date
1995/12
Journal
Hybridoma
Volume
14
Issue
6
Pages
551-556
Description
The P3 murine monoclonal antibody (MAb) was generated by immunizing BALB/c mice with NeuGcGM3 included into liposomes. The specificity of this MAb was defined by an enzyme-linked immunosorbent assay and immunostaining on thin-layer chromatograms. P3 MAb binds to NeuGc-containing gangliosides and was shown also to react with sulfated glycolipids. A preliminary immunohistochemical study showed that the P3 MAb was able to recognize antigens expressed in human breast tumors.
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Scholar articles
AM Vazquez, M Alfonso, B Lanne, KA Karlsson, A Carr… - Hybridoma, 1995